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INSULIN-LIKE GROWTH FACTOR-1 STIMULATION OF HYPOTHALAMIC KISS-1 GENE EXPRESSION IS MEDIATED BY AKT: EFFECT OF ALCOHOL
Kisspeptin, as well as insulin-like growth factor-1 (IGF-1), act centrally to stimulate luteinizing hormone-releasing hormone (LHRH) secretion at puberty. IGF-1 can induce KiSS-1 gene expression as an early pubertal event; however, the signaling pathway mediating this effect is not known. Since alco...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823990/ https://ncbi.nlm.nih.gov/pubmed/20034543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.12.030 |
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