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INSULIN-LIKE GROWTH FACTOR-1 STIMULATION OF HYPOTHALAMIC KISS-1 GENE EXPRESSION IS MEDIATED BY AKT: EFFECT OF ALCOHOL

Kisspeptin, as well as insulin-like growth factor-1 (IGF-1), act centrally to stimulate luteinizing hormone-releasing hormone (LHRH) secretion at puberty. IGF-1 can induce KiSS-1 gene expression as an early pubertal event; however, the signaling pathway mediating this effect is not known. Since alco...

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Detalhes bibliográficos
Main Authors: Hiney, Jill K., Srivastava, Vinod K., Dees, W. Les
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823990/
https://ncbi.nlm.nih.gov/pubmed/20034543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.12.030
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