Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear

In the medial prefrontal cortex, the prelimbic area is emerging as a major modulator of fear behavior, but the mechanisms remain unclear. Using a selective neocortical knockout mouse, virally mediated prelimbic cortical-specific gene deletion, and pharmacological rescue with a TrkB agonist, we exami...

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Detaylı Bibliyografya
Asıl Yazarlar: Choi, Dennis C., Maguschak, Kimberly A., Ye, Keqiang, Jang, Sung-Wuk, Myers, Karyn M., Ressler, Kerry J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823921/
https://ncbi.nlm.nih.gov/pubmed/20133801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909359107
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