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Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear
In the medial prefrontal cortex, the prelimbic area is emerging as a major modulator of fear behavior, but the mechanisms remain unclear. Using a selective neocortical knockout mouse, virally mediated prelimbic cortical-specific gene deletion, and pharmacological rescue with a TrkB agonist, we exami...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823921/ https://ncbi.nlm.nih.gov/pubmed/20133801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909359107 |
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