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Synthetic design of strong promoters

We have taken a synthetic biology approach to the generation and screening of transcription factor binding sites for activity in human cells. All possible 10-mer DNA sequences were printed on microarrays as 100-mers containing 10 repeats of the same sequence in tandem, yielding an oligonucleotide li...

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Detalhes bibliográficos
Main Authors: Schlabach, Michael R., Hu, Jimmy K., Li, Mamie, Elledge, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823900/
https://ncbi.nlm.nih.gov/pubmed/20133776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914803107
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