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Synthetic design of strong promoters
We have taken a synthetic biology approach to the generation and screening of transcription factor binding sites for activity in human cells. All possible 10-mer DNA sequences were printed on microarrays as 100-mers containing 10 repeats of the same sequence in tandem, yielding an oligonucleotide li...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823900/ https://ncbi.nlm.nih.gov/pubmed/20133776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914803107 |
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