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Formation and dissociation of M(1) muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules

G-protein–coupled receptors (GPCRs) are the largest family of transmembrane signaling proteins in the human genome. Events in the GPCR signaling cascade have been well characterized, but the receptor composition and its membrane distribution are still generally unknown. Although there is evidence th...

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Detalhes bibliográficos
Main Authors: Hern, Jonathan A., Baig, Asma H., Mashanov, Gregory I., Birdsall, Berry, Corrie, John E. T., Lazareno, Sebastian, Molloy, Justin E., Birdsall, Nigel J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823895/
https://ncbi.nlm.nih.gov/pubmed/20133736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907915107
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