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Analysis of the cellular mechanism underlying inhibition of EAE after treatment with anti-NKG2A F(ab′)(2)

Autoimmune encephalomyelitis may be ameliorated experimentally by enhancing NK cell-mediated elimination of activated autoreactive T cells through a mutation that interrupts the interaction between Qa-1(b) and CD94/NKG2A. Here we evaluate the ability of an anti-NKG2A F(ab′)(2) Ab to enhance eliminat...

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Detalhes bibliográficos
Main Authors: Leavenworth, Jianmei W., Schellack, Carola, Kim, Hye-Jung, Lu, Linrong, Spee, Pieter, Cantor, Harvey
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823885/
https://ncbi.nlm.nih.gov/pubmed/20133787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914732107
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