A truncated lipoglycan from mycobacteria with altered immunological properties

Maintenance of cell-wall integrity in Mycobacterium tuberculosis is essential and is the target of several antitubercular drugs. For example, ethambutol targets arabinogalactan and lipoarabinomannan (LAM) biosynthesis through the inhibition of several arabinofuranosyltransferases. Apart from their r...

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Detalhes bibliográficos
Main Authors: Birch, Helen L., Alderwick, Luke J., Appelmelk, Ben J., Maaskant, Janneke, Bhatt, Apoorva, Singh, Albel, Nigou, Jerome, Eggeling, Lothar, Geurtsen, Jeroen, Besra, Gurdyal S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823879/
https://ncbi.nlm.nih.gov/pubmed/20133807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915082107
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