Hybridization thermodynamics of NimbleGen Microarrays

BACKGROUND: While microarrays are the predominant method for gene expression profiling, probe signal variation is still an area of active research. Probe signal is sequence dependent and affected by probe-target binding strength and the competing formation of probe-probe dimers and secondary structu...

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Main Authors: Mueckstein, Ulrike, Leparc, Germán G, Posekany, Alexandra, Hofacker, Ivo, Kreil, David P
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823707/
https://ncbi.nlm.nih.gov/pubmed/20085625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-35
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