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Mechanisms of mutagenesis in the Escherichia coli mutator mutD5: role of DNA mismatch repair.

To investigate the mechanisms of spontaneous mutation in the Escherichia coli mutD5 mutator strain, 502 mutations generated in this strain in the N-terminal part of the lacI gene were sequenced (i-d mutations). Since the mutator strength of this strain depends on the medium in which it grows, mutati...

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Bibliographic Details
Main Author: Schaaper, R M
Format: Artigo
Language:Inglês
Published: 1988
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC282368/
https://ncbi.nlm.nih.gov/pubmed/3054881
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