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Rpe65 as a modifier gene for inherited retinal degeneration
Light accelerates progression of retinal degeneration in many animal models of retinitis pigmentosa (RP). A sequence variant in the Rpe65 gene (Rpe65(450Leu) or Rpe65(450Met)) can act as a modulator of light-damage susceptibility in mice by influencing the kinetics of rhodopsin regeneration and thus...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2006
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823586/ https://ncbi.nlm.nih.gov/pubmed/16519667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2006.04639.x |
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