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RPE65: Role in the visual cycle, human retinal disease, and gene therapy

RPE65 is an isomerohydrolase expressed in retinal pigment epithelium. It is critical for the regeneration of the visual pigment necessary for both rod and cone-mediated vision. Mutations in human RPE65 cause Leber’s congenital amaurosis and other forms of autosomal recessive retinitis pigmentosa whi...

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Detalhes bibliográficos
Main Authors: Cai, Xue, Conley, Shannon M., Naash, Muna I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821785/
https://ncbi.nlm.nih.gov/pubmed/19373675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13816810802626399
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