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Structural Hierarchy of Regulatory Elements in the Folding and Transport of an Intestinal Multidomain Protein
Human intestinal lactase-phlorizin hydrolase, LPH, encompasses four homologous domains, which presumably have evolved from two subsequent duplications of one ancestral gene. The profragment, LPHα, comprises homologous domains I and II and functions as an intramolecular chaperone in the context of th...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823554/ https://ncbi.nlm.nih.gov/pubmed/19955176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.060780 |
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