Protein Phosphatase 2A Regulates Interleukin-2 Receptor Complex Formation and JAK3/STAT5 Activation

Reversible protein phosphorylation plays a key role in interleukin-2 (IL-2) receptor-mediated activation of Janus tyrosine kinase 3 (JAK3) and signal transducer and activator of transcription 5 (STAT5) in lymphocytes. Although the mechanisms governing IL-2-induced tyrosine phosphorylation and activa...

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Detalhes bibliográficos
Main Authors: Ross, Jeremy A., Cheng, Hanyin, Nagy, Zsuzsanna S., Frost, Jeffrey A., Kirken, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823499/
https://ncbi.nlm.nih.gov/pubmed/19923221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.053843
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