Signal Transducer and Activator of Transcription 5b (Stat5b) Serine 193 Is a Novel Cytokine-induced Phospho-regulatory Site That Is Constitutively Activated in Primary Hematopoietic Malignancies

Signal transducer and activator of transcription 5b (Stat5b) is a critical node in the signaling network downstream of external (cytokines or growth factors) or internal (oncogenic tyrosine kinases) stimuli. Maximum transcriptional activation of Stat5b requires both tyrosine and serine phosphorylati...

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Main Authors: Mitra, Abhisek, Ross, Jeremy A., Rodriguez, Georgialina, Nagy, Zsuzsanna S., Wilson, Harry L., Kirken, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351328/
https://ncbi.nlm.nih.gov/pubmed/22442148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.319756
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