Molecular Dissection of Human Interleukin-31-mediated Signal Transduction through Site-directed Mutagenesis

Interleukin (IL)-31 is a recently described cytokine, preferentially produced by T helper 2 lymphocytes and associated with skin diseases, such as atopic dermatitis. IL-31 is a member of the four α-helix bundle cytokine family and is related to the IL-6 subgroup. Its heterodimeric membrane receptor...

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Bibliografiske detaljer
Main Authors: Le Saux, Sabine, Rousseau, François, Barbier, Fabien, Ravon, Elisa, Grimaud, Linda, Danger, Yannic, Froger, Josy, Chevalier, Sylvie, Gascan, Hugues
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823401/
https://ncbi.nlm.nih.gov/pubmed/19920145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.049189
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