Proline cis/trans-Isomerase Pin1 Regulates Peroxisome Proliferator-activated Receptor γ Activity through the Direct Binding to the Activation Function-1 Domain

The important roles of a nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) are widely accepted in various biological processes as well as metabolic diseases. Despite the worldwide quest for pharmaceutical manipulation of PPARγ activity through the ligand-binding domain, very litt...

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Détails bibliographiques
Auteurs principaux: Fujimoto, Yoshito, Shiraki, Takuma, Horiuchi, Yuji, Waku, Tsuyoshi, Shigenaga, Akira, Otaka, Akira, Ikura, Tsuyoshi, Igarashi, Kazuhiko, Aimoto, Saburo, Tate, Shin-ichi, Morikawa, Kosuke
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2010
Sujets:
Mechanisms of Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823398/
https://ncbi.nlm.nih.gov/pubmed/19996102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.055095
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