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Prolyl Isomerase Pin1 Regulates Transcription Factor LSF (TFCP2) by Facilitating Dephosphorylation at Two Serine-Proline Motifs
Transcription factor LSF is essential for cell cycle progression, being required for activating expression of the thymidylate synthase (Tyms) gene at the G1/S transition. We previously established that phosphorylation of LSF in early G1 at Ser-291 and Ser-309 inhibits its transcriptional activity an...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2951187/ https://ncbi.nlm.nih.gov/pubmed/20682773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.078808 |
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