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Role of disulfide bridges in determining the biological activity of interleukin 3.

Total chemical synthesis of analog proteins was used to examine the requirement for specific disulfide bridges for the biological activity of interleukin 3 (IL-3), a growth factor that stimulates multiple lineages of hemopoietic cells. Four structural analogs of the mature, 140 amino acid murine IL-...

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Detalhes bibliográficos
Main Authors: Clark-Lewis, I, Hood, L E, Kent, S B
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC282306/
https://ncbi.nlm.nih.gov/pubmed/3263644
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