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Nkx2.5/Csx Represses Myofibroblast Differentiation

Myofibroblasts are known to play key roles in wound healing and fibrosis. They are thought to arise de novo from fibroblasts, and are characterized by induction of α–smooth muscle actin (α-SMA) expression. The homeobox transcription factor Csx/Nkx2.5 is critical in heart development and cardiogenesi...

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Detalhes bibliográficos
Main Authors: Hu, Biao, Wu, Yue Ming, Wu, Zhe, Phan, Sem H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822983/
https://ncbi.nlm.nih.gov/pubmed/19395679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0404OC
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