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Nkx2.5/Csx Represses Myofibroblast Differentiation
Myofibroblasts are known to play key roles in wound healing and fibrosis. They are thought to arise de novo from fibroblasts, and are characterized by induction of α–smooth muscle actin (α-SMA) expression. The homeobox transcription factor Csx/Nkx2.5 is critical in heart development and cardiogenesi...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Thoracic Society
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822983/ https://ncbi.nlm.nih.gov/pubmed/19395679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0404OC |
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