Analyzing mRNA expression identifies Smad3 as a microRNA-140 target regulated only at protein level

mRNA profiling is routinely used to identify microRNA targets, however, this high-throughput technology is not suitable for identifying targets regulated only at protein level. Here, we have developed and validated a novel methodology based on computational analysis of promoter sequences combined wi...

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Bibliographische Detailangaben
Hauptverfasser: Pais, Helio, Nicolas, Francisco Esteban, Soond, Surinder M., Swingler, Tracey E., Clark, Ian M., Chantry, Andrew, Moulton, Vincent, Dalmay, Tamas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2010
Schlagworte:
Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822914/
https://ncbi.nlm.nih.gov/pubmed/20071455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1701210
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