Prolactin Inhibits Expression of the Proto-oncogene BCL6 in Breast Cancer through a Stat5a Dependent Mechanism

Stat5a mediates prolactin-induced differentiation of mammary epithelia, and loss of Stat5 signaling in human breast cancer is associated with undifferentiated histology and poor prognosis. The transcriptional repressor BCL6 shares DNA target sequences with Stat5, disrupts differentiation of breast e...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Tran, Thai H., Utama, Fransiscus E., Lin, Justin, Yang, Ning, Sjolund, Ashley B., Ryder, Amy, Johnson, Kevin J., Neilson, Lynn M., Liu, Chengbao, Brill, Kristin L., Rosenberg, Anne L., Witkiewicz, Agnieszka K., Rui, Hallgeir
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2010
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822876/
https://ncbi.nlm.nih.gov/pubmed/20124477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2314
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