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Polarization of Chemoattractant Receptor Signaling During Neutrophil Chemotaxis

Morphologic polarity is necessary for chemotaxis of mammalian cells. As a probe of intracellular signals responsible for this asymmetry, the pleckstrin homology domain of the AKT protein kinase (or protein kinase B), tagged with the green fluorescent protein (PHAKT-GFP), was expressed in neutrophils...

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Detalhes bibliográficos
Main Authors: Servant, Guy, Weiner, Orion D., Herzmark, Paul, Balla, Tamás, Sedat, John W., Bourne, Henry R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822871/
https://ncbi.nlm.nih.gov/pubmed/10669415
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