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Polarization of Chemoattractant Receptor Signaling During Neutrophil Chemotaxis

Morphologic polarity is necessary for chemotaxis of mammalian cells. As a probe of intracellular signals responsible for this asymmetry, the pleckstrin homology domain of the AKT protein kinase (or protein kinase B), tagged with the green fluorescent protein (PHAKT-GFP), was expressed in neutrophils...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Servant, Guy, Weiner, Orion D., Herzmark, Paul, Balla, Tamás, Sedat, John W., Bourne, Henry R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822871/
https://ncbi.nlm.nih.gov/pubmed/10669415
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