Cystatin E/M suppresses legumain activity and invasion of human melanoma

BACKGROUND: High activity of cysteine proteases such as legumain and the cathepsins have been shown to facilitate growth and invasion of a variety of tumor types. In breast cancer, several recent studies have indicated that loss of the cysteine protease inhibitor cystatin E/M leads to increased grow...

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Bibliographic Details
Main Authors: Briggs, Jon J, Haugen, Mads H, Johansen, Harald T, Riker, Adam I, Abrahamson, Magnus, Fodstad, Øystein, Mælandsmo, Gunhild M, Solberg, Rigmor
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822816/
https://ncbi.nlm.nih.gov/pubmed/20074384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-17
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