MT1-MMP is required for myeloid cell fusion via regulation of Rac1 signaling

Cell fusion is essential for fertilization, myotube formation, and inflammation. Macrophages fuse in various circumstances but the molecular signals involved in the distinct steps of their fusion are not fully characterized. Using null mice and derived cells, we show that the protease MT1-MMP is nec...

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Detalhes bibliográficos
Main Authors: Gonzalo, Pilar, Guadamillas, Marta C., Hernández-Riquer, Mª Victoria, Pollán, Ángela, Grande-García, Araceli, Bartolomé, Rubén A., Vasanji, Amit, Ambrogio, Chiara, Chiarle, Roberto, Teixidó, Joaquín, Risteli, Juha, Apte, Suneel S., del Pozo, Miguel A., Arroyo, Alicia G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822729/
https://ncbi.nlm.nih.gov/pubmed/20152179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.11.012
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