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Inhibitory Odorant Signaling in Mammalian Olfactory Receptor Neurons

Odorants inhibit as well as excite olfactory receptor neurons (ORNs) in many species of animals. Cyclic nucleotide-dependent activation of canonical mammalian ORNs is well established but it is still unclear how odorants inhibit these cells. Here we further implicate phosphoinositide-3-kinase (PI3K)...

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Hlavní autoři: Ukhanov, Kirill, Corey, Elizabeth A., Brunert, Daniela, Klasen, Katharina, Ache, Barry W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822701/
https://ncbi.nlm.nih.gov/pubmed/20032232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00980.2009
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