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Phosphoinositide-3-Kinase Is the Primary Mediator of Phosphoinositide-Dependent Inhibition in Mammalian Olfactory Receptor Neurons

Odorants inhibit as well as excite primary olfactory receptor neurons (ORNs) in many animal species. Growing evidence suggests that inhibition of mammalian ORNs is mediated by phosphoinositide (PI) signaling through activation of phosphoinositide 3-kinase (PI3K), and that canonical adenylyl cyclase...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Ukhanov, Kirill, Corey, Elizabeth, Ache, Barry W.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826873/
https://ncbi.nlm.nih.gov/pubmed/27147969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00097
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