Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes.

Immunoglobulin heavy-chain switching is effected by a DNA recombination event that replaces the C mu gene with one of the other heavy-chain constant-region (CH) genes located 3' to the C mu gene. How the specificity of this event is controlled is unknown. However, it has been shown that IgM+ ce...

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Hauptverfasser: Stavnezer, J, Radcliffe, G, Lin, Y C, Nietupski, J, Berggren, L, Sitia, R, Severinson, E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC282261/
https://ncbi.nlm.nih.gov/pubmed/2459714
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