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Statistics of protein-DNA binding and the total number of binding sites for a transcription factor in the mammalian genome

BACKGROUND: Transcription factor (TF)-DNA binding loci are explored by analyzing massive datasets generated with application of Chromatin Immuno-Precipitation (ChIP)-based high-throughput sequencing technologies. These datasets suffer from a bias in the information about binding loci availability, s...

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Detalhes bibliográficos
Main Authors: Kuznetsov, Vladimir A, Singh, Onkar, Jenjaroenpun, Piroon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822526/
https://ncbi.nlm.nih.gov/pubmed/20158869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-S1-S12
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