8-pCPT-cGMP stimulates αβγ-ENaC activity in oocytes as an external ligand requiring specific nucleotide moieties

Epithelial sodium channels (ENaC) are regulated by protein kinase A, in addition to a broad spectrum of other protein kinases. It is not clear whether cGMP/PKG signaling might regulate ENaC activity. We examined the responses of αβγ-ENaC channels expressed in Xenopus oocytes to 8-(4-chlorophenylthio...

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Bibliographic Details
Main Authors: Nie, Hong-Guang, Zhang, Wei, Han, Dong-Yun, Li, Qing-Nan, Li, Jun, Zhao, Run-Zhen, Su, Xue-Feng, Peng, Ji-Bin, Ji, Hong-Long
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822513/
https://ncbi.nlm.nih.gov/pubmed/20007351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00307.2009
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