Impaired oxidative metabolism and inflammation are associated with insulin resistance in ERα-deficient mice

Impaired estrogen action is associated with the metabolic syndrome in humans. We sought to determine whether impaired estrogen action in female C57Bl6 mice, produced by whole body Esr1 ablation, could recapitulate aspects of this syndrome, including inflammation, insulin resistance, and obesity. Ind...

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Hauptverfasser: Ribas, Vicent, Nguyen, M. T. Audrey, Henstridge, Darren C., Nguyen, Anh-Khoi, Beaven, Simon W., Watt, Matthew J., Hevener, Andrea L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2010
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822483/
https://ncbi.nlm.nih.gov/pubmed/19920214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00504.2009
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