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Influence of glucosamine on glomerular mesangial cell turnover: implications for hyperglycemia and hexosamine pathway flux

Cells exposed to high glucose may undergo hypertrophy, proliferation, and apoptosis, but the role of hexosamine flux in mediating these effects has not been fully elucidated. Accordingly, we studied the effects of glucose and glucosamine on rat glomerular mesangial cells (MC) turnover. Compared with...

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Autors principals: James, Leighton R., Le, Catherine, Scholey, James W.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822474/
https://ncbi.nlm.nih.gov/pubmed/19903862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00232.2009
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