Oleanane Triterpenoid CDDO-Me Inhibits Growth and Induce Apoptosis in Prostate Cancer Cells through a ROS-dependent Mechanism

CDDO-Me, a synthetic triterpenoid derived from oleanolic acid, is a promising anticancer agent that has shown strong activity against a wide variety cancer types in vitro and in vivo. We have previously shown that CDDO-Me induces apoptosis in prostate cancer cells irrespective of their hormonal stat...

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Main Authors: Deeb, Dorrah, Gao, Xiaohua, Jiang, Hao, Janic, Branislava, Arbab, Ali S., Rojanasakul, Yon, Dulchavsky, Scott A., Gautam, Subhash C.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822351/
https://ncbi.nlm.nih.gov/pubmed/19782051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.09.006
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