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Cooperative Nature of Gating Transitions in K(+) Channels as seen from Dynamic Importance Sampling Calculations

The growing dataset of K(+) channel x-ray structures provides an excellent opportunity to begin a detailed molecular understanding of voltage-dependent gating. These structures, while differing in sequence, represent either a stable open or closed state. However, an understanding of the molecular de...

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Detalhes bibliográficos
Main Authors: Denning, Elizabeth J., Woolf, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822122/
https://ncbi.nlm.nih.gov/pubmed/19950367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22632
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