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Enhanced glutathione biosynthetic capacity promotes resistance to As3+-induced apoptosis

Trivalent arsenite (As3+) is a known human carcinogen capable of inducing both cellular transformation and apoptotic cell death by mechanisms involving the production of reactive oxygen species. The tripeptide antioxidant glutathione (GSH) constitutes a vital cellular defense mechanism against oxida...

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Hlavní autoři: Thompson, James A., Franklin, Christopher C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822119/
https://ncbi.nlm.nih.gov/pubmed/20006689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2009.12.004
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