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Enhanced glutathione biosynthetic capacity promotes resistance to As3+-induced apoptosis
Trivalent arsenite (As3+) is a known human carcinogen capable of inducing both cellular transformation and apoptotic cell death by mechanisms involving the production of reactive oxygen species. The tripeptide antioxidant glutathione (GSH) constitutes a vital cellular defense mechanism against oxida...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822119/ https://ncbi.nlm.nih.gov/pubmed/20006689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2009.12.004 |
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