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Chronic Exposure to Zinc Chromate Induces Centrosome Amplification and Spindle Assembly Checkpoint Bypass in Human Lung Fibroblasts

Hexavalent chromium (Cr(VI)) compounds are known human lung carcinogens. Solubility plays an important role in its carcinogenicity with the particulate or insoluble form being the most potent. Of the particulate Cr(VI) compounds, zinc chromate appears to be the most potent carcinogen, however, very...

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Main Authors: Holmes, Amie L., Wise, Sandra S., Pelsue, Stephen C., Aboueissa, AbouEl-Makarim, Lingle, Wilma, Salisbury, Jeffery, Gallagher, Jamie, Wise, John Pierce
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822114/
https://ncbi.nlm.nih.gov/pubmed/20030412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900360w
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