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Chronic Exposure to Zinc Chromate Induces Centrosome Amplification and Spindle Assembly Checkpoint Bypass in Human Lung Fibroblasts

Hexavalent chromium (Cr(VI)) compounds are known human lung carcinogens. Solubility plays an important role in its carcinogenicity with the particulate or insoluble form being the most potent. Of the particulate Cr(VI) compounds, zinc chromate appears to be the most potent carcinogen, however, very...

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Detalhes bibliográficos
Main Authors: Holmes, Amie L., Wise, Sandra S., Pelsue, Stephen C., Aboueissa, AbouEl-Makarim, Lingle, Wilma, Salisbury, Jeffery, Gallagher, Jamie, Wise, John Pierce
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822114/
https://ncbi.nlm.nih.gov/pubmed/20030412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900360w
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