Inhibition of acquired immunodeficiency syndrome virus by oligodeoxynucleoside methylphosphonates.

Antisense oligodeoxynucleotides containing internucleoside methylphosphonate linkages were examined for their ability to inhibit human immunodeficiency virus (HIV)-induced syncytium formation and virus expression. HIV inhibitory activity was found to be dependent on both chain length and the number...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Sarin, P S, Agrawal, S, Civeira, M P, Goodchild, J, Ikeuchi, T, Zamecnik, P C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282208/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3174646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.20.7448
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