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Roles for Catharsis S, L, and B in Insulitis and Diabetes in the NOD Mouse

We developed a panel of non-obese diabetic (NOD) mice deficient in major lysosomal cysteine proteases (cathepsins S, L and B) to identify protease enzymes essential for autoimmune diabetes. Null alleles for cathepsins (Cts) S, L or B were introgressed onto the NOD genetic background with 19 Idd mark...

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Hlavní autoři:	Hsing, Lianne C., Kirk, Elizabeth A., McMillen, Timothy S., Hsiao, Shuo-Hung, Caldwell, Mark, Houston, Barbara, Rudensky, Alexander Y., LeBoeuf, Renee C.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	2009
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2822044/ https://ncbi.nlm.nih.gov/pubmed/19664906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2009.07.003
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Roles for Catharsis S, L, and B in Insulitis and Diabetes in the NOD Mouse

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