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Deficiency of lymphotoxin-α does not exacerbate high-fat diet-induced obesity but does enhance inflammation in mice

Lymphotoxin-α (LTα) is secreted by lymphocytes and acts through tumor necrosis factor-α receptors and the LTβ receptor. Our goals were to determine whether LT has a role in obesity and investigate whether LT contributes to the link between obesity and adipose tissue lymphocyte accumulation. LT defic...

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Détails bibliographiques
Auteurs principaux: Pamir, Nathalie, McMillen, Timothy S., Edgel, Kimberly A., Kim, Francis, LeBoeuf, Renée C.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330720/
https://ncbi.nlm.nih.gov/pubmed/22318945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00447.2011
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