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Association between the response to TNF-antagonists and plasma type I interferon activity and interferon-beta/alpha ratios in rheumatoid arthritis patients: a post-hoc analysis of a predominantly Hispanic Cohort

OBJECTIVE: Despite substantial clinical efficacy of tumor necrosis factor-α (TNF)-antagonist therapy in patients with rheumatoid arthritis (RA), some patients respond poorly to such agents. Since an interferon (IFN) signature is variably expressed among RA patients, we investigated whether plasma ty...

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Autori principali: Mavragani, Clio P., La, Dan T., Stohl, William, Crow, Mary K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821991/
https://ncbi.nlm.nih.gov/pubmed/20112385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27226
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