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Vacuolar ATPase Regulates Surfactant Secretion in Rat Alveolar Type II Cells by Modulating Lamellar Body Calcium

Lung surfactant reduces surface tension and maintains the stability of alveoli. How surfactant is released from alveolar epithelial type II cells is not fully understood. Vacuolar ATPase (V-ATPase) is the enzyme responsible for pumping H(+) into lamellar bodies and is required for the processing of...

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Autors principals: Chintagari, Narendranath Reddy, Mishra, Amarjit, Su, Lijing, Wang, Yang, Ayalew, Sahlu, Hartson, Steven D., Liu, Lin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821907/
https://ncbi.nlm.nih.gov/pubmed/20169059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009228
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