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Vacuolar ATPase Regulates Surfactant Secretion in Rat Alveolar Type II Cells by Modulating Lamellar Body Calcium

Lung surfactant reduces surface tension and maintains the stability of alveoli. How surfactant is released from alveolar epithelial type II cells is not fully understood. Vacuolar ATPase (V-ATPase) is the enzyme responsible for pumping H(+) into lamellar bodies and is required for the processing of...

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Détails bibliographiques
Auteurs principaux: Chintagari, Narendranath Reddy, Mishra, Amarjit, Su, Lijing, Wang, Yang, Ayalew, Sahlu, Hartson, Steven D., Liu, Lin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821907/
https://ncbi.nlm.nih.gov/pubmed/20169059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009228
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