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Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes

Nuclear pore complexes have recently been shown to play roles in gene activation, however their potential involvement in metazoan transcription remains unclear. Here we show that the nucleoporins Sec13, Nup98 and Nup88, as well as a group of FG-repeat nucleoporins, bind to the Drosophila genome at f...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Capelson, Maya, Liang, Yun, Schulte, Roberta, Mair, William, Wagner, Ulrich, Hetzer, Martin W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821818/
https://ncbi.nlm.nih.gov/pubmed/20144761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.12.054
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