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Angiotensin-(1-7)-ACE2 attenuates reactive oxygen species formation to Angiotensin II within the cell nucleus

The angiotensin type 1 receptor (AT(1)R) is highly expressed on renal nuclei and stimulates reactive oxygen species (ROS). It is not known whether other functional components of the angiotensin (Ang) system regulate the nuclear Ang II-AT(1)R-ROS pathway. Therefore, we examined the expression of Ang...

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Main Authors: Gwathmey, TanYa M., Pendergrass, Karl D., Reid, Sean D., Rose, James C., Diz, Debra I., Chappell, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821807/
https://ncbi.nlm.nih.gov/pubmed/19948986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.141622
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