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Angiotensin-(1-7)-ACE2 attenuates reactive oxygen species formation to Angiotensin II within the cell nucleus

The angiotensin type 1 receptor (AT(1)R) is highly expressed on renal nuclei and stimulates reactive oxygen species (ROS). It is not known whether other functional components of the angiotensin (Ang) system regulate the nuclear Ang II-AT(1)R-ROS pathway. Therefore, we examined the expression of Ang...

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Autori principali: Gwathmey, TanYa M., Pendergrass, Karl D., Reid, Sean D., Rose, James C., Diz, Debra I., Chappell, Mark C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821807/
https://ncbi.nlm.nih.gov/pubmed/19948986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.141622
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