Hypoxia-Inducible Factor-1 as a Therapeutic Target in Endometrial Cancer Management

In the Western world, endometrial cancer (EC) is the most common malignant tumor of the female genital tract. Solid tumors like EC outgrow their vasculature resulting in hypoxia. Tumor hypoxia is important because it renders an aggressive phenotype and leads to radio- and chemo-therapy resistance. H...

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Библиографические подробности
Главные авторы: Seeber, Laura M. S., Zweemer, Ronald P., Verheijen, René H. M., van Diest, Paul J.
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2010
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Review Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821774/
https://ncbi.nlm.nih.gov/pubmed/20169098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/580971
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