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A Mutation in the β-Myosin Rod Associated With Hypertrophic Cardiomyopathy Has an Unexpected Molecular Phenotype

Hypertrophic cardiomyopathy (HCM) is a common, autosomal dominant disorder primarily characterized by left ventricular hypertrophy and is the leading cause of sudden cardiac death in youth. HCM is caused by mutations in several sarcomeric proteins, with mutations in MYH7, encoding β-MyHC, being the...

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Main Authors: Armel, Thomas Z., Leinwand, Leslie A.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821741/
https://ncbi.nlm.nih.gov/pubmed/19913502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.11.062
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